Immunogen
The antiserum was produced against synthesized peptide derived from human AMOTL1. AA range:441-490
Specificity
Angiomotin-L1 Polyclonal Antibody detects endogenous levels of Angiomotin-L1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],
Function
similarity:Belongs to the angiomotin family.,
Protein name
Angiomotin-like protein 1
Abbreviation
Angiomotin-L1
Other name
AMOTL1; Angiomotin-like protein 1
Human protein sequence Database
Q8IY63
Mouse protein sequence database
Q9D4H4
Rat protein sequence database
Cellular localization
Cell junction, tight junction .
Tissue expression
Brain,Epithelium,Muscle,Skeletal muscle,Skin,Spleen,Testis,Thymus,
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