Molecular weight (DA)
48kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 160-240
Specificity
ZPI Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2010],
Function
function:Inhibits factor Xa activity in the presence of protein Z, calcium and phospholipid.,similarity:Belongs to the serpin family.,tissue specificity:Expressed by the liver and secreted in plasma.,
Gene Name
SERPINA10 ZPI UNQ707/PRO1358
Protein name
Protein Z-dependent protease inhibitor (PZ-dependent protease inhibitor) (PZI) (Serpin A10)
Human protein sequence Database
Q9UK55
Mouse protein sequence database
Q8R121
Rat protein sequence database
Q62975
Cellular localization
Secreted.
Tissue expression
Expressed by the liver and secreted in plasma.
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