Molecular weight (DA)
49kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ARMX1. AA range:1-50
Specificity
ARMCX1 Polyclonal Antibody detects endogenous levels of ARMCX1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
armadillo repeat containing, X-linked 1(ARMCX1) Homo sapiens This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome. [provided by RefSeq, Jul 2008],
Function
similarity:Contains 3 ARM repeats.,tissue specificity:Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carcinomas.,
Protein name
Armadillo repeat-containing X-linked protein 1
Other name
ARMCX1; ALEX1; AD032; Armadillo repeat-containing X-linked protein 1; ARM protein lost in epithelial cancers on chromosome X 1; Protein ALEX1
Human protein sequence Database
Q9P291
Mouse protein sequence database
Q9CX83
Rat protein sequence database
Cellular localization
Mitochondrion . Mitochondrion outer membrane ; Single-pass membrane protein .
Tissue expression
Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carcinomas.
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