Molecular weight (DA)
38kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ARMX3. AA range:291-340
Specificity
ARMCX3 Polyclonal Antibody detects endogenous levels of ARMCX3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
armadillo repeat containing, X-linked 3(ARMCX3) Homo sapiens This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],
Function
similarity:Contains 3 ARM repeats.,
Protein name
Armadillo repeat-containing X-linked protein 3
Other name
ARMCX3; ALEX3; BM-017; Armadillo repeat-containing X-linked protein 3; ARM protein lost in epithelial cancers on chromosome X 3; Protein ALEX3
Human protein sequence Database
Q9UH62
Mouse protein sequence database
Q8BHS6
Rat protein sequence database
Q5XID7
Cellular localization
Mitochondrion outer membrane ; Single-pass membrane protein . Cytoplasm . Nucleus .
Tissue expression
Bone marrow,Brain,Epithelium,Kidney,Liver,Retina,Skin,Testis,