Molecular weight (DA)
60kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ARSF. AA range:301-350
Specificity
Arylsulfatase F Polyclonal Antibody detects endogenous levels of Arylsulfatase F protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene is a member of the sulfatase family, and more specifically, the arylsulfatase subfamily. Members of the subfamily share similarity in sequence and splice sites, and are clustered together on chromosome X, suggesting that they are derived from recent gene duplication events. Sulfatases are essential for the correct composition of bone and cartilage matrix. The activity of this protein, unlike that of arylsulfatase E, is not inhibited by warfarin. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jan 2011],
Function
cofactor:Binds 1 calcium ion per subunit.,enzyme regulation:Not inhibited by DHEAS or warfarin.,PTM:The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.,similarity:Belongs to the sulfatase family.,
Protein name
Arylsulfatase F
Abbreviation
Arylsulfatase F
Other name
ARSF; Arylsulfatase F; ASF
Human protein sequence Database
P54793
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Fetal brain,Kidney,
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