Molecular weight (DA)
18kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
THIOM Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. [provided by RefSeq, Jul 2008],
Function
function:Has an anti-apoptotic function and plays an important role in the regulation of mitochondrial membrane potential. Could be involved in the resistance to anti-tumor agents. Possesses a dithiol-reducing activity.,similarity:Belongs to the thioredoxin family.,similarity:Contains 1 thioredoxin domain.,subunit:Monomer.,tissue specificity:Widely expressed in adult (at protein level) and fetal tissues.,
Protein name
Thioredoxin, mitochondrial (MTRX) (Mt-Trx) (Thioredoxin-2)
Fields
>>NOD-like receptor signaling pathway;>>Parkinson disease;>>Salmonella infection;>>Fluid shear stress and atherosclerosis
Human protein sequence Database
Q99757
Mouse protein sequence database
P97493
Rat protein sequence database
P97615
Cellular localization
Mitochondrion .
Tissue expression
Widely expressed in adult (at protein level) and fetal tissues.
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