Molecular weight (DA)
97kD
Immunogen
The antiserum was produced against synthesized peptide derived from human CEP97. AA range:581-630
Specificity
Cep97 Polyclonal Antibody detects endogenous levels of Cep97 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Collaborates with cep110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of cep110 to the centrosome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 IQ domain.,similarity:Contains 6 LRR (leucine-rich) repeats.,subunit:Interacts with CALM1 and CEP110.,
Function
function:Collaborates with cep110, being involved in the suppression of a cilia assembly program. Required for correct spindle formation and has a role in cytokinesis. Required for recruitment of cep110 to the centrosome.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 IQ domain.,similarity:Contains 6 LRR (leucine-rich) repeats.,subunit:Interacts with CALM1 and CEP110.,
Protein name
Centrosomal protein of 97 kDa
Other name
CEP97; LRRIQ2; Centrosomal protein of 97 kDa; Cep97; Leucine-rich repeat and IQ domain-containing protein 2
Human protein sequence Database
Q8IW35
Mouse protein sequence database
Q9CZ62
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Recruited at the distal end of the mother centriole by MPHOSPH9. .
Tissue expression
Lung,Skin,Testis,
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