Molecular weight (DA)
65kD
Immunogen
Synthesized peptide derived from the Internal region of human Glypican-5.
Specificity
Glypican-5 Polyclonal Antibody detects endogenous levels of Glypican-5 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008],
Function
function:Cell surface proteoglycan that bears heparan sulfate.,similarity:Belongs to the glypican family.,tissue specificity:In adult, primarily expressed in the brain. Also detected in fetal brain, lung and liver.,
Other name
GPC5; Glypican-5
Human protein sequence Database
P78333
Mouse protein sequence database
Q8CAL5
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side .; [Secreted glypican-5]: Secreted, extracellular space .
Tissue expression
In adult, primarily expressed in the brain. Also detected in fetal brain, lung and liver.