Molecular weight (DA)
55kD
Immunogen
The antiserum was produced against synthesized peptide derived from human IFIT1. AA range:41-90
Specificity
IFI-56K Polyclonal Antibody detects endogenous levels of IFI-56K protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein containing tetratricopeptide repeats that was originally identified as induced upon treatment with interferon. The encoded protein may inhibit viral replication and translational initiation. This gene is located in a cluster on chromosome 10 with five other closely related genes. There is a pseudogene for this gene on chromosome 13. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Aug 2012],
Function
induction:By interferons.,similarity:Belongs to the IFIT family.,similarity:Contains 10 TPR repeats.,
Protein name
Interferon-induced protein with tetratricopeptide repeats 1
Other name
IFIT1; G10P1; IFI56; IFNAI1; ISG56; Interferon-induced protein with tetratricopeptide repeats 1; IFIT-1; Interferon-induced 56 kDa protein; IFI-56K; P56
Human protein sequence Database
P09914
Mouse protein sequence database
Q64282
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Prostate,Synovial membrane tissue,
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