Molecular weight (DA)
25kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MOL1A. AA range:101-150
Specificity
Mob1A Polyclonal Antibody detects endogenous levels of Mob1A protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],
Function
function:Stimulates the kinase activity of STK38L.,similarity:Belongs to the MOB1/phocein family.,subunit:Binds STK38L.,
Protein name
MOB kinase activator 1B
Other name
MOB1B; MOB4A; MOBKL1A; MOB kinase activator 1B; Mob1 homolog 1A; Mob1A; Mob1B; Mps one binder kinase activator-like 1A
Fields
>>Hippo signaling pathway;>>Hippo signaling pathway - multiple species
Human protein sequence Database
Q7L9L4
Mouse protein sequence database
Q8BPB0
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus .
Tissue expression
Adrenal gland, bone marrow, brain, lung, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, uterus, colon with mucosa, fetal brain and fetal liver.
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