Molecular weight (DA)
140kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MOV10L1. AA range:318-367
Specificity
MOV10L1 Polyclonal Antibody detects endogenous levels of MOV10L1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Mov10 RISC complex RNA helicase like 1(MOV10L1) Homo sapiens This gene is similar to a mouse gene that encodes a putative RNA helicase and shows testis-specific expression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009],
Function
alternative products:Additional isoforms seem to exist,function:Putative RNA helicase. Isoform 1 may play a role in male germ cell development.,similarity:Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.,tissue specificity:Isoform 1 is specifically expressed in testis.,
Protein name
Putative helicase Mov10l1
Other name
MOV10L1; Putative helicase Mov10l1; Moloney leukemia virus 10-like protein 1; MOV10-like protein 1
Human protein sequence Database
Q9BXT6
Mouse protein sequence database
Q99MV5
Rat protein sequence database
Cellular localization
Cytoplasm . Component of the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. .
Tissue expression
[Isoform 1]: Specifically expressed in testis.
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