Molecular weight (DA)
20kD
Immunogen
Synthesized peptide derived from MRP-L17 . at AA range: 100-180
Specificity
MRP-L17 Polyclonal Antibody detects endogenous levels of MRP-L17 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the ribosomal protein L17P family.,tissue specificity:Detected in adrenal gland, mammary gland and adipose tissue.,
Protein name
39S ribosomal protein L17 mitochondrial
Other name
MRPL17; LIP2; 39S ribosomal protein L17; mitochondrial; L17mt; MRP-L17; LYST-interacting protein 2
Human protein sequence Database
Q9NRX2
Mouse protein sequence database
Q9D8P4
Rat protein sequence database
Cellular localization
Mitochondrion .
Tissue expression
Detected in adrenal gland, mammary gland and adipose tissue.