Molecular weight (DA)
11kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 20-100
Specificity
DIRC1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene consists of two exons and encodes a 104aa protein. Disruption of this gene by translocation t(2;3)(q33;q21) is associated with familial clear cell renal cancer. [provided by RefSeq, Sep 2010],
Function
disease:A chromosomal aberration involving DIRC1 is found in familial renal cell carcinoma 1-related translocation t(2;3)(q33;q21) (RCC1).,tissue specificity:Expressed at low steady-state level in adult placenta, testis, ovary, prostate, fetal kidney, spleen and skeletal muscle.,
Protein name
Disrupted in renal carcinoma protein 1 (Disrupted in renal cancer protein)
Human protein sequence Database
Q969H9
Mouse protein sequence database
Rat protein sequence database
Tissue expression
Expressed at low steady-state level in adult placenta, testis, ovary, prostate, fetal kidney, spleen and skeletal muscle.
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