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PBR Polyclonal Antibody

Polyclonal antibody

Specification

BYab-04062

  • 50UL $180 100UL $255
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Product introduction>

Host
Reactiveness
Use
Molecular weight (DA)
20kD
Immunogen
Synthesized peptide derived from PBR . at AA range: 90-170
Specificity
PBR Polyclonal Antibody detects endogenous levels of PBR protein.
Source
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Background
Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein. [provided by RefSeq, Feb 2012],
Function
protein targeting, protein targeting to mitochondrion, porphyrin metabolic process, porphyrin biosynthetic process,heme biosynthetic process, ion transport, anion transport, mitochondrial transport, intracellular protein transport,apoptosis, mitochondrion organization, protein localization, steroid metabolic process, cell death, cell proliferation,programmed cell death, protein transport, death, protein import, heterocycle biosynthetic process, regulation of lipid transport, regulation of sterol transport, regulation of cholesterol transport, tetrapyrrole metabolic process,tetrapyrrole biosynthetic process, protein localization in organelle, cellular protein localization, heme metabolic process, pigment metabolic process, nitrogen compound biosynthetic process, establishment of protein localization,pigment biosynthetic process, intracellular transport, cofactor metabolic process, cofacto
Gene Name
TSPO
Protein name
Translocator protein
Abbreviation
PBR
Other name
TSPO; BZRP; MBR; Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR
Fields
>>Neuroactive ligand-receptor interaction;>>Cholesterol metabolism;>>Human T-cell leukemia virus 1 infection
Human gene ID
706
Human protein sequence Database
P30536
Mouse gene ID
Mouse protein sequence database
Rat gene ID
Rat protein sequence database
Cellular localization
Mitochondrion membrane ; Multi-pass membrane protein .
Tissue expression
Found in many tissue types. Expressed at the highest levels under normal conditions in tissues that synthesize steroids.
Storage
-20°C/1 year

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PBR Polyclonal Antibody

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