Molecular weight (DA)
26kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MOBL3. AA range:1-50
Specificity
Phocein Polyclonal Antibody detects endogenous levels of Phocein protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene was identified based on its similarity with the mouse counterpart. Studies of the mouse counterpart suggest that the expression of this gene may be regulated during oocyte maturation and preimplantation following zygotic gene activation. Alternatively spliced transcript variants encoding distinct isoforms have been observed. Naturally occurring read-through transcription occurs between this locus and the neighboring locus HSPE1.[provided by RefSeq, Feb 2011],
Function
PTM:Phosphorylated on serine residues.,similarity:Belongs to the MOB1/phocein family.,subcellular location:In a perinuclear punctate pattern. Associated with membranes and the Golgi stacks.,subunit:Binds STRN4 (By similarity). Binds STRN and STRN3. Part of a ternary complex containing MOBKL3, STRN and/or STRN3 and PPA2.,
Protein name
MOB-like protein phocein
Other name
MOB4; MOB3; MOBKL3; PHOCN; PREI3; CGI-95; MOB-like protein phocein; 2C4D; Class II mMOB1; Mob1 homolog 3; Mob3; Mps one binder kinase activator-like 3; Preimplantation protein 3
Human protein sequence Database
Q9Y3A3
Mouse protein sequence database
Q6PEB6
Rat protein sequence database
Q9QYW3
Cellular localization
Cytoplasm, perinuclear region . Membrane ; Peripheral membrane protein . Golgi apparatus, Golgi stack membrane ; Peripheral membrane protein . In a perinuclear punctate pattern. Associated with membranes and the Golgi stacks.
Tissue expression
Adrenal gland,Brain,Trachea,Urinary bladder,
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