Molecular weight (DA)
25kD
Immunogen
Synthesized peptide derived from Ribosomal Protein L10A . at AA range: 30-110
Specificity
Ribosomal Protein L10A Polyclonal Antibody detects endogenous levels of Ribosomal Protein L10A protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes
Function
similarity:Belongs to the ribosomal protein L1P family.,
Protein name
60S ribosomal protein L10a
Abbreviation
Ribosomal Protein L10A
Other name
RPL10A; NEDD6; 60S ribosomal protein L10a; CSA-19; Neural precursor cell expressed developmentally down-regulated protein 6; NEDD-6
Fields
>>Ribosome;>>Coronavirus disease - COVID-19
Human protein sequence Database
P62906
Mouse protein sequence database
P53026
Rat protein sequence database
P62907
Cellular localization
nucleus,nucleolus,cytoplasm,cytosol,ribosome,focal adhesion,large ribosomal subunit,membrane,cytosolic large ribosomal subunit,extracellular exosome,
Tissue expression
Breast,Cervix,