Molecular weight (DA)
13kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RPL34. AA range:41-90
Specificity
Ribosomal Protein L34 Polyclonal Antibody detects endogenous levels of Ribosomal Protein L34 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L34E family of ribosomal proteins. It is located in the cytoplasm. This gene originally was thought to be located at 17q21, but it has been mapped to 4q. Overexpression of this gene has been observed in some cancer cells. Alternative splicing results in multiple transcript variants, all encoding the same isoform. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Feb 2016],
Function
similarity:Belongs to the ribosomal protein L34e family.,
Protein name
60S ribosomal protein L34
Abbreviation
Ribosomal Protein L34
Other name
RPL34; 60S ribosomal protein L34
Fields
>>Ribosome;>>Coronavirus disease - COVID-19
Human protein sequence Database
P49207
Mouse protein sequence database
Q9D1R9
Rat protein sequence database
P11250
Cellular localization
Cytoplasm, cytosol . Cytoplasm . Endoplasmic reticulum . Detected on cytosolic polysomes (PubMed:25957688). Detected in ribosomes that are associated with the rough endoplasmic reticulum (By similarity). .
Tissue expression
Bone,Epithelium,Eye,Ovary,