Molecular weight (DA)
16kD
Immunogen
Synthetic peptide from human protein at AA range: 80-141
Specificity
The antibody detects endogenous Calcitonin
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.,function:CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.,function:Katacalcin is a potent plasma calcium-lowering peptide.,online information:Calcitonin entry,similarity:Belongs to the calcitonin family.,
Function
function:Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.,function:CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. It also elevates platelet cAMP.,function:Katacalcin is a potent plasma calcium-lowering peptide.,online information:Calcitonin entry,similarity:Belongs to the calcitonin family.,
Protein name
Calcitonin [Cleaved into: Calcitonin; Katacalcin (Calcitonin carboxyl-terminal peptide) (CCP) (PDN-21)]
Other name
Calcitonin [Cleaved into: Calcitonin; Katacalcin (Calcitonin carboxyl-terminal peptide;CCP;PDN-21)]
Human protein sequence Database
P01258
Mouse protein sequence database
P70160
Rat protein sequence database
Cellular localization
Secreted.
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