Molecular weight (DA)
48kD
Immunogen
The antiserum was produced against synthesized peptide derived from human PPP1R7. AA range:136-185
Specificity
Sds22 Polyclonal Antibody detects endogenous levels of Sds22 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein subunit that regulates the activity of the serine/threonine phosphatase, protein phosphatase-1. The encoded protein is required for completion of the mitotic cycle and for targeting protein phosphatase-1 to mitotic kinetochores. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
Function
function:Regulatory subunit of protein phosphatase 1.,similarity:Belongs to the SDS22 family.,similarity:Contains 10 LRR (leucine-rich) repeats.,subunit:Interacts with PPP1CA, PPP1CB and PPP1CC/PPP1G isoform 1.,tissue specificity:Widely expressed.,
Protein name
Protein phosphatase 1 regulatory subunit 7
Other name
PPP1R7; SDS22; Protein phosphatase 1 regulatory subunit 7; Protein phosphatase 1 regulatory subunit 22
Human protein sequence Database
Q15435
Mouse protein sequence database
Q3UM45
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Widely expressed.
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