Molecular weight (DA)
48kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 140-220
Specificity
IP6K1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the inositol phosphokinase family. The encoded protein may be responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2011],
Function
catalytic activity:ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).,catalytic activity:ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.,function:Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.,similarity:Belongs to the inositol phosphokinase (IPK) family.,
Gene Name
IP6K1 IHPK1 KIAA0263
Protein name
Inositol hexakisphosphate kinase 1 (InsP6 kinase 1) (EC 2.7.4.21) (Inositol hexaphosphate kinase 1)
Fields
>>Phosphatidylinositol signaling system
Human protein sequence Database
Q92551
Mouse protein sequence database
Q6PD10
Rat protein sequence database
Q9ESM0
Cellular localization
Cytoplasm . Nucleus .
Tissue expression
Bone marrow,Eye,Hippocampus,
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