Molecular weight (DA)
57kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Specificity
VEZF1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. ZNF161 is a C2H2-type zinc finger protein (Koyano-Nakagawa et al., 1994 [PubMed 8035792]). See MIM 603971 for general information on zinc finger proteins.[supplied by OMIM, Sep 2008],
Function
function:Possible transcription factor. Specifically binds to the CT/GC-rich region of the interleukin-3 promoter and mediates tax transactivation of IL-3.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 6 C2H2-type zinc fingers.,subunit:Interacts with ARHGAP22.,tissue specificity:Ubiquitously expressed. Highest levels in skeletal muscle and kidney.,
Gene Name
VEZF1 DB1 ZNF161
Protein name
Vascular endothelial zinc finger 1 (Putative transcription factor DB1) (Zinc finger protein 161)
Human protein sequence Database
Q14119
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Ubiquitously expressed. Highest levels in skeletal muscle and kidney.
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