Molecular weight (DA)
28kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 80-160
Specificity
RT15 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encod
Function
similarity:Belongs to the ribosomal protein S15P family.,subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,
Gene Name
MRPS15 RPMS15 DC37
Protein name
28S ribosomal protein S15, mitochondrial (MRP-S15) (S15mt)
Human protein sequence Database
P82914
Mouse protein sequence database
Q9DC71
Rat protein sequence database
Q5XI37
Cellular localization
Mitochondrion .
Tissue expression
Aorta endothelial cell,Dendritic cell,Skin,