Molecular weight (DA)
46kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 240-320
Specificity
RM37 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the ribosomal protein S30/L37 family.,
Gene Name
MRPL37 MRPL2 RPML2 HSPC235
Protein name
39S ribosomal protein L37, mitochondrial (L37mt) (MRP-L37) (39S ribosomal protein L2, mitochondrial) (L2mt) (MRP-L2)
Human protein sequence Database
Q9BZE1
Mouse protein sequence database
Q921S7
Rat protein sequence database
Q6AXT0
Cellular localization
Mitochondrion .
Tissue expression
Placenta,Skeletal muscle,Umbilical cord blood,
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