Molecular weight (DA)
27kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CPNS2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.,similarity:Contains 4 EF-hand domains.,subcellular location:Translocates to the plasma membrane upon calcium binding.,subunit:Heterodimer of a large (catalytic) and a small (regulatory) subunit.,
Function
function:Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation for activity.,similarity:Contains 4 EF-hand domains.,subcellular location:Translocates to the plasma membrane upon calcium binding.,subunit:Heterodimer of a large (catalytic) and a small (regulatory) subunit.,
Protein name
Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2)
Human protein sequence Database
Q96L46
Mouse protein sequence database
Q9D7J7
Rat protein sequence database
Cellular localization
Cytoplasm . Cell membrane . Translocates to the plasma membrane upon calcium binding. .
Tissue expression
Urinary bladder carcinoma,
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