Molecular weight (DA)
24kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CHAC1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016],
Function
similarity:Belongs to the chaC family.,
Protein name
Cation transport regulator-like protein 1 (Blocks Notch protein) (Botch)
Fields
>>Glutathione metabolism;>>Metabolic pathways
Human protein sequence Database
Q9BUX1
Mouse protein sequence database
Q8R3J5
Rat protein sequence database
B3STU3
Cellular localization
Cytoplasm, cytosol . Golgi apparatus, trans-Golgi network .
Tissue expression
Liver,Muscle,
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