Molecular weight (DA)
15kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
RABP1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. [provided by RefSeq, Jul 2008],
Function
domain:Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.,function:Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.,similarity:Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.,
Protein name
Cellular retinoic acid-binding protein 1 (Cellular retinoic acid-binding protein I) (CRABP-I)
Human protein sequence Database
P29762
Mouse protein sequence database
P62965
Rat protein sequence database
P62966
Cellular localization
Cytoplasm .
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