Molecular weight (DA)
19kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CKLF7 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor that regulates G1/S transition in the cell cycle, and epidermal growth factor receptor/protein kinase B signaling during tumor pathogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],
Function
similarity:Belongs to the chemokine-like factor family.,similarity:Contains 1 MARVEL domain.,tissue specificity:Highly expressed in leukocytes.,
Protein name
CKLF-like MARVEL transmembrane domain-containing protein 7 (Chemokine-like factor superfamily member 7)
Human protein sequence Database
Q96FZ5
Mouse protein sequence database
Q9ESD6
Rat protein sequence database
Cellular localization
Membrane; Multi-pass membrane protein.
Tissue expression
Highly expressed in leukocytes.
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