Molecular weight (DA)
143kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CNTP4 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the neurexin protein family. Members of this family function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. This protein may also play a role in proper neurotransmission in the dopaminergic and GABAergic systems and mutations in this gene may be associated with certain psychiatric illnesses. A polymorphism in an intron of this gene may be associated with longevity. [provided by RefSeq, Apr 2016],
Function
similarity:Belongs to the neurexin family.,similarity:Contains 1 F5/8 type C domain.,similarity:Contains 1 fibrinogen C-terminal domain.,similarity:Contains 2 EGF-like domains.,similarity:Contains 4 laminin G-like domains.,
Gene Name
CNTNAP4 CASPR4 KIAA1763
Protein name
Contactin-associated protein-like 4 (Cell recognition molecule Caspr4)
Human protein sequence Database
Q9C0A0
Mouse protein sequence database
Q99P47
Rat protein sequence database
Cellular localization
Cell junction, synapse, presynaptic cell membrane ; Single-pass type I membrane protein . Specifically present within the presynaptic compartment of synapses. .
Tissue expression
Brain,Testis,
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