Molecular weight (DA)
12kD
Immunogen
Synthesized peptide derived from part region of human protein AA range: 1-50
Specificity
DYLT3 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
dynein light chain Tctex-type 3(DYNLT3) Homo sapiens This gene encodes a member of a subclass of dynein light chains. The encoded protein homodimerizes and forms the light chain component of the cytoplasmic dynein motor protein complex. This protein may be important for binding dynein to specific cargos including the spindle checkpoint protein BUB3. This protein may also function independently of dynein as a transcriptional modulator. Pseudogenes of this gene are found on chromosomes 2 and 20.[provided by RefSeq, Mar 2010],
Function
caution:Was originally (PubMed:8004092) thought to be a candidate for RP3.,similarity:Belongs to the dynein light chain Tctex-type family.,
Gene Name
DYNLT3 TCTE1L TCTE1XL
Protein name
Dynein light chain Tctex-type 3 (Protein 91/23) (T-complex-associated testis-expressed 1-like)
Fields
>>Salmonella infection
Human protein sequence Database
P51808
Mouse protein sequence database
P56387
Rat protein sequence database
Cellular localization
Nucleus. Cytoplasm, cytoskeleton. Chromosome, centromere, kinetochore. Colocalizes with BUB3 at kinetochores specifically during prometaphase.
Tissue expression
Placenta,Subthalamic nucleus,
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