Molecular weight (DA)
26kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
FOLR3 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the folate receptor (FOLR) family of proteins, which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. Expression of this gene may be elevated in ovarian and primary peritoneal carcinoma. This gene is present in a gene cluster on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],
Function
function:Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. Isoform Short does not bind folate.,PTM:Eight disulfide bonds are present.,similarity:Belongs to the folate receptor family.,tissue specificity:Spleen, thymus, bone marrow, ovarian carcinoma, and uterine carcinoma.,
Protein name
Folate receptor gamma (FR-gamma) (Folate receptor 3)
Fields
>>Antifolate resistance;>>Endocytosis
Human protein sequence Database
P41439
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Spleen, thymus, bone marrow, ovarian carcinoma, and uterine carcinoma.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车