Molecular weight (DA)
15kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
VPREB Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene belongs to the immunoglobulin superfamily and is expressed selectively at the early stages of B cell development, namely, in proB and early preB cells. This gene encodes the iota polypeptide chain that is associated with the Ig-mu chain to form a molecular complex which is expressed on the surface of pre-B cells. The complex is thought to regulate Ig gene rearrangements in the early steps of B-cell differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015],
Function
function:Associates with the Ig-mu chain to form a molecular complex that is expressed on the surface of pre-B-cells. This complex presumably regulates ig gene rearrangements in the early steps of B-cell differentiation.,similarity:Belongs to the immunoglobulin superfamily.,subunit:Associates non-covalently with IGLL1.,tissue specificity:Only expressed by pre-B-cells.,
Protein name
Immunoglobulin iota chain (CD179 antigen-like family member A) (Protein VPreB1) (V(pre)B protein) (VpreB protein) (CD antigen CD179a)
Human protein sequence Database
P12018
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Endoplasmic reticulum .
Tissue expression
Only expressed by pre-B-cells.
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