Molecular weight (DA)
39kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 150-230
Specificity
LHX8 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the LIM homeobox family of proteins, which are involved in patterning and differentiation of various tissue types. These proteins contain two tandemly repeated cysteine-rich double-zinc finger motifs known as LIM domains, in addition to a DNA-binding homeodomain. This family member is a transcription factor that plays a role in tooth morphogenesis. It is also involved in oogenesis and in neuronal differentiation. This gene is a candidate gene for cleft palate, and it is also associated with odontoma formation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012],
Function
function:Transcription factor involved in differentiation of certain neurons and mesenchymal cells.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,
Protein name
LIM/homeobox protein Lhx8 (LIM homeobox protein 8)
Human protein sequence Database
Q68G74
Mouse protein sequence database
O35652
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Peripheral blood,Testis,
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