Molecular weight (DA)
50kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 330-410
Specificity
LS14A Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Mar 2008],
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the LSM14 family.,
Gene Name
LSM14A C19orf13 FAM61A RAP55 RAP55A
Protein name
Protein LSM14 homolog A (Protein FAM61A) (Protein SCD6 homolog) (Putative alpha-synuclein-binding protein) (AlphaSNBP) (RNA-associated protein 55A) (hRAP55) (hRAP55A)
Human protein sequence Database
Q8ND56
Mouse protein sequence database
Q8K2F8
Rat protein sequence database
Cellular localization
Cytoplasm, P-body . Cytoplasm, cytoskeleton, spindle . Cytoplasm, Stress granule .
Tissue expression
Brain,Epithelium,Mammary gland,Pancreas,Platelet,Testis,
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