Molecular weight (DA)
21kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 20-100
Specificity
PGRC1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a putative membrane-associated progesterone steroid receptor. The protein is expressed predominantly in the liver and kidney. [provided by RefSeq, Mar 2010],
Function
domain:The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 107 and 131.,function:Receptor for progesterone.,similarity:Belongs to the cytochrome b5 family. MAPR subfamily.,similarity:Contains 1 cytochrome b5 heme-binding domain.,tissue specificity:Widely expressed, with highest expression in liver and kidney.,
Gene Name
PGRMC1 HPR6.6 PGRMC
Protein name
Membrane-associated progesterone receptor component 1 (mPR)
Human protein sequence Database
O00264
Mouse protein sequence database
O55022
Rat protein sequence database
P70580
Cellular localization
Microsome membrane ; Single-pass membrane protein . Smooth endoplasmic reticulum membrane ; Single-pass membrane protein . Mitochondrion outer membrane ; Single-pass membrane protein ; Extracellular side .
Tissue expression
Widely expressed, with highest expression in liver and kidney. Expressed by endometrial glands and stroma (at protein level) (PubMed:23793472).
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