Molecular weight (DA)
16kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 70-150
Specificity
MAL Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3. [provided by RefSeq, May 2012],
Function
developmental stage:Expressed in the intermediate and late stages of T-cell differentiation.,function:Could be an important component in vesicular trafficking cycling between the Golgi complex and the apical plasma membrane. Could be involved in myelin biogenesis and/or myelin function.,PTM:Lipoprotein.,similarity:Belongs to the MAL family.,similarity:Contains 1 MARVEL domain.,
Protein name
Myelin and lymphocyte protein (T-lymphocyte maturation-associated protein)
Human protein sequence Database
P21145
Mouse protein sequence database
O09198
Rat protein sequence database
Q64349
Cellular localization
Membrane; Multi-pass membrane protein.
Tissue expression
Brain,Lung,Lymphocyte,Placenta,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车