Molecular weight (DA)
226kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 680-760
Specificity
MYO10 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
myosin X(MYO10) Homo sapiens This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myosins contain the basic domains of conventional myosins and are further distinguished from class members by their tail domains. This gene functions as an actin-based molecular motor and plays a role in integration of F-actin and microtubule cytoskeletons during meiosis. [provided by RefSeq, Dec 2011],
Function
function:Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity). Plays a role in regions of dynamic actin.,similarity:Contains 1 FERM domain.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 1 MyTH4 domain.,similarity:Contains 2 PH domains.,similarity:Contains 3 IQ domains.,
Protein name
Unconventional myosin-X (Unconventional myosin-10)
Fields
>>Fc gamma R-mediated phagocytosis;>>Pathogenic Escherichia coli infection
Human protein sequence Database
Q9HD67
Mouse protein sequence database
F8VQB6
Rat protein sequence database
D3ZJP6
Cellular localization
Cytoplasm, cytosol . Cell projection, lamellipodium . Cell projection, ruffle . Cytoplasm, cytoskeleton . Cell projection, filopodium tip . Cytoplasm, cell cortex . Cell projection, filopodium membrane ; Peripheral membrane protein . May be in an inactive, monomeric conformation in the cytosol. Detected in cytoplasmic punctae and in cell projections. Colocalizes with actin fibers. Undergoes forward and rearward movements within filopodia. Interacts with microtubules.
Tissue expression
Ubiquitous.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车