Molecular weight (DA)
260kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 1880-1960
Specificity
NBAS Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
IHC-p 1:50-300. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly. [provided by RefSeq, Oct 2012],
Function
sequence caution:Translated as stop.,sequence caution:Translation N-terminally extended.,similarity:Contains 2 WD repeats.,tissue specificity:Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small inntestine and thymus. Up-regulated together with N-myc in some neuroblastoma cell lines.,
Protein name
Neuroblastoma-amplified sequence (Neuroblastoma-amplified gene protein)
Human protein sequence Database
A2RRP1
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm . Endoplasmic reticulum . Endoplasmic reticulum membrane; Peripheral membrane protein .
Tissue expression
Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblastoma cell lines.
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