Molecular weight (DA)
55kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 350-430
Specificity
NPTXR Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat pentraxin receptor is an integral membrane protein that is thought to mediate neuronal uptake of the snake venom toxin, taipoxin, and its transport into the synapses. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for mouse and human, based on strong sequence conservation amongst these species. [provided by RefSeq, Jul 2008],
Function
cofactor:Binds 2 calcium ions per subunit.,similarity:Contains 1 pentaxin domain.,
Protein name
Neuronal pentraxin receptor
Human protein sequence Database
O95502
Mouse protein sequence database
Q99J85
Rat protein sequence database
O35764
Cellular localization
Membrane ; Single-pass type II membrane protein .
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