Molecular weight (DA)
47kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 170-250
Specificity
NPTX1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
NPTX1 is a member of the neuronal pentraxin gene family. Neuronal pentraxin 1 is similar to the rat NP1 gene which encodes a binding protein for the snake venom toxin taipoxin. Human NPTX1 mRNA is exclusively localized to the nervous system. [provided by RefSeq, Jul 2008],
Function
cofactor:Binds 2 calcium ions per subunit.,function:May mediate uptake of degraded synaptic material which could play an important role in synaptic remodeling. Can mediate the neuronal and glial uptake of the snake venom toxin taipoxin.,similarity:Contains 1 pentaxin domain.,
Protein name
Neuronal pentraxin-1 (NP1) (Neuronal pentraxin I) (NP-I)
Human protein sequence Database
Q15818
Mouse protein sequence database
Q62443
Rat protein sequence database
P47971
Cellular localization
Cytoplasmic vesicle, secretory vesicle .
Tissue expression
Chondrosarcoma,Hippocampus,
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