Molecular weight (DA)
10kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 10-90
Specificity
S10AD Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is widely expressed in various types of tissues with a high expression level in thyroid gland. In smooth muscle cells, this protein co-expresses with other family members in the nucleus and in stress fibers, suggesting diverse functions in signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Function
similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,tissue specificity:Expressed in heart and skeletal muscle.,
Protein name
Protein S100-A13 (S100 calcium-binding protein A13)
Human protein sequence Database
Q99584
Mouse protein sequence database
P97352
Rat protein sequence database
Cellular localization
Cytoplasm. Secreted. Secretion is mediated by exposure to stress and requires copper ions.
Tissue expression
Expressed in heart and skeletal muscle.
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