Molecular weight (DA)
22kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 50-130
Specificity
RAB1A Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq, Oct 2008],
Function
function:Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.,PTM:Phosphorylated by CDC2 kinase during mitosis.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:May interact with YIPF5.,
Protein name
Ras-related protein Rab-1A (YPT1-related protein)
Fields
>>Autophagy - animal;>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases;>>Pathogenic Escherichia coli infection;>>Legionellosis
Human protein sequence Database
P62820
Mouse protein sequence database
P62821
Rat protein sequence database
Q6NYB7
Cellular localization
Golgi apparatus . Endoplasmic reticulum . Early endosome . Cytoplasm, cytosol . Membrane . Melanosome . Alternates between membrane-associated and cytosolic forms. .
Tissue expression
Brain,Colon,Placenta,Platelet,Tongue,
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