Molecular weight (DA)
24kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 80-160
Specificity
RAB28 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the Rab subfamily of Ras-related small GTPases. The encoded protein may be involved in regulating intracellular trafficking. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 9 and X. [provided by RefSeq, Apr 2009],
Function
similarity:Belongs to the small GTPase superfamily. Rab family.,tissue specificity:Isoform S is detected in most tissues investigated (cortex, liver, kidney, skeletal muscle, adipose tissue, testis and urothelium), whereas isoform L is predominant in testis.,
Protein name
Ras-related protein Rab-28
Human protein sequence Database
P51157
Mouse protein sequence database
Q99KL7
Rat protein sequence database
P51158
Cellular localization
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, cytoskeleton, cilium basal body. Expressed in the basal body and ciliary rootlet of the photoreceptors. .
Tissue expression
Isoform S is detected in most tissues investigated: cortex, liver, kidney, skeletal muscle, adipose tissue, testis, urothelium, lung, bone marrow and retinal pigment epithelium (RPE). Isoform L 2 is widely and abundantly expressed all tissues. Isoform 3 is highly expressed in heart, lung, bone marrow, retina, brain, and RPE.