Molecular weight (DA)
16kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 10-90
Specificity
RGS21 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.[supplied by OMIM, Nov 2008],
Function
function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.,similarity:Contains 1 RGS domain.,tissue specificity:Expressed ubiquitously.,
Protein name
Regulator of G-protein signaling 21 (RGS21)
Human protein sequence Database
Q2M5E4
Mouse protein sequence database
Rat protein sequence database
Cellular localization
cytoplasm,plasma membrane,
Tissue expression
Expressed ubiquitously.
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