Molecular weight (DA)
139kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 320-400
Specificity
RGS22 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.,similarity:Contains 2 RGS domains.,
Function
function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.,similarity:Contains 2 RGS domains.,
Protein name
Regulator of G-protein signaling 22 (RGS22)
Human protein sequence Database
Q8NE09
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus . Expressed in the cytoplasm of spermatogonia and spermatocytes. In spermatids, also expressed in the nucleus.
Tissue expression
Testis-specific. Expressed in Leydig cells and spermatogenic cells from the spermatogonia to spermatid stages (at protein level).