Molecular weight (DA)
23kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Specificity
RHOJ Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes one of the many small GTP-binding proteins in the Rho family shown to be associated with focal adhesions in endothelial cells (PMID: 21148427, 22103495). The encoded protein is activated by vascular endothelial growth factor and may regulate angiogenesis. [provided by RefSeq, Dec 2011],
Function
function:GTP-binding protein with GTPase activity. Elicits the formation of F-actin-rich structures in fibroblasts and is involved in the regulation of cell morphology.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Interacts with the CRIB domains of proteins such as Pak1 and Was/Wasp.,
Gene Name
RHOJ ARHJ RASL7B RHOI TCL
Protein name
Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Fields
>>Salmonella infection
Human protein sequence Database
Q9H4E5
Mouse protein sequence database
Q9ER71
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor ; Cytoplasmic side . Localization to the plasma membrane is regulated by GLUL. .
Tissue expression
Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver.
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