Molecular weight (DA)
49kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 90-170
Specificity
SEP10 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the septin family of cytoskeletal proteins with GTPase activity. This protein localizes to the cytoplasm and nucleus and displays GTP-binding and GTPase activity. A pseudogene for this gene is located on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012],
Function
function:Involved in cytokinesis (Potential). Can bind to GTP and exert GTPase activity.,similarity:Belongs to the septin family.,tissue specificity:Ubiquitous. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines.,
Human protein sequence Database
Q9P0V9
Mouse protein sequence database
Q8C650
Rat protein sequence database
Q5PQK1
Cellular localization
Cytoplasm . Cytoplasm, cytoskeleton . Using a GFP-fusion protein, detected in the nucleus. .
Tissue expression
Widely expressed. Abundantly expressed in heart and kidney, placenta, skeletal muscles, liver and lung, as well as various tumor cell lines.
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