Molecular weight (DA)
31kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
VAX2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a homeobox protein and is almost exclusively expressed in the ventral portion of the retina during development. In mouse studies, this gene was found to be required for the correct formation of the optic fissure and other aspects of retinal development. [provided by RefSeq, Sep 2008],
Function
developmental stage:Expressed in the ventral part of the optic vesicles at 7 week dpc.,function:Plays a crucial role in eye development and, in particular, in the specification of the ventral optic vesicle (By similarity). May be a regulator of axial polarization in the retina.,similarity:Belongs to the EMX homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
Protein name
Ventral anterior homeobox 2
Human protein sequence Database
Q9UIW0
Mouse protein sequence database
Q9WTP9
Rat protein sequence database
Q9JLZ9
Cellular localization
Nucleus .
Tissue expression
Teratocarcinoma,Uterus,
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