Molecular weight (DA)
24kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
WFDC1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
WAP four-disulfide core domain 1(WFDC1) Homo sapiens This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. This gene is downregulated in many cancer types and may be involved in the inhibition of cell proliferation. The encoded protein may also play a role in the susceptibility of certain CD4 memory T cells to human immunodeficiency virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
Function
function:Has growth inhibitory activity.,similarity:Contains 1 WAP domain.,
Protein name
WAP four-disulfide core domain protein 1 (Prostate stromal protein ps20) (ps20 growth inhibitor)
Human protein sequence Database
Q9HC57
Mouse protein sequence database
Q9ESH5
Rat protein sequence database
O70280
Cellular localization
Secreted .
Tissue expression
Colon,Kidney,Placenta,Prostate,Stomach,Uterus,
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