Molecular weight (DA)
91kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
S39AA Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A10 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008],
Function
function:May act as a zinc-influx transporter.,miscellaneous:High levels of expression are correlated with invasiveness in several breast cancer lines.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the ZIP transporter (TC 2.A.5) family.,
Gene Name
SLC39A10 KIAA1265 ZIP10
Protein name
Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10)
Fields
>>Alzheimer disease;>>Parkinson disease
Human protein sequence Database
Q9ULF5
Mouse protein sequence database
Q6P5F6
Rat protein sequence database
Cellular localization
Membrane ; Multi-pass membrane protein .
Tissue expression
Brain,Colon carcinoma,Epithelium,Prostate,Testis,
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