Molecular weight (DA)
92kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 250-330
Specificity
BACH2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK.,similarity:Belongs to the bZIP family. CNC subfamily.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer of BACH2 and Maf-related transcription factors.,tissue specificity:B-cell specific.,
Function
function:Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK.,similarity:Belongs to the bZIP family. CNC subfamily.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer of BACH2 and Maf-related transcription factors.,tissue specificity:B-cell specific.,
Protein name
Transcription regulator protein BACH2 (BTB and CNC homolog 2)
Human protein sequence Database
Q9BYV9
Mouse protein sequence database
P97303
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus . Nucleocytoplasmic shuttling is controlled by phosphorylation. .
Tissue expression
B-cell specific.
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